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High-speed analysis of powder and tablets with hyperspectral imaging

Date Announced: 06 Sep 2021

A common application of NIR spectroscopy is the identification of the active compound or active pharmaceutical ingredient (API) present in a tablet or drug.

A French company, Indatech has developed a new technology for powder and tablet analysis that relies on the innovative use of optical probes using several optical fibres to measure the surface of the sample. All the fibres are connected to a Specim NIR hyperspectral imaging system.

Currently Indatech provides solutions mainly for the pharma, biotech and chemical industry. Their core business is the high-speed inspection of a tablet (hardness, API, homogeneity) and powder either in manufacturing or in process development phase.

Challenging approach meets hyperspectral imaging

The challenge in their approach is the need to measure multiple optical fibres at the same time as well as they must be able to change the configuration of the measurement. “Before hyperspectral, we tested standard spectrometer connected to an optical multiplexer but in the end, the measurement took too long,” says Fabien. “So, we decided to try the hyperspectral imaging and we found out that the pushbroom imaging is the best approach because the spectra are measured in a single shot without any moving parts and the resolution can also be adapted.”

“We started discussing with another manufacturer before we met Mr Timo Hyvärinen at a Pharma Congress in the United States. He presented me the company, as well as the technology behind it, and I’ve been completely convinced of the performance and the quality ever since. Specim is very reactive and always tries to find a solution in case of a specific need. The products are robust since the company has acquired a long experience. The products have the little things that make the difference in terms of performance and quality.” says Fabien.

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Specim are represented in the UK and Ireland by Quantum Design. 


Luke Nicholls

E-mail: luke@qd-uki.co.uk

Web Site: www.qd-uki.co.uk

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