Images collected using an SRS microscope show that normal brain contains sparse cells with bundles of nerve fibers, called axons (left), but brain tumor tissue is full of cells in a disordered pattern (right). Though evident under the microscope, during surgery they are very difficult to differentiate, making it hard for a surgeon to know where the tumor stops. Raman tools could potentially provide real-time analysis with the same kind of accuracy as the path-lab micropscope. Credit: PRNewsFoto/University of Michigan Health. |