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| (A) A top-down view of the RPE layer as seen by clinical OCT. Although the image is zoomed in to the scale of single cells, it is difficult to visualize the cells. (B) AO-OCT provides a more detailed image of the RPE layer, but the cells are obscured by speckle. (C) There is a remarkable improvement in RPE cell visualization gained by applying AI to the speckled AO-OCT image. Each dark area represents a single RPE cell. Credit: Vineeta Das/NEI. (Front page image: RPE cells as seen with high-resolution microscopy. Credit: Kapil Bharti/NEI.) |
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